Guide of principles in main dog and cat skin’s affections topical aplications

Authors: Flavius Faltinski, Romeo T. Cristina, Eugenia Dumitrescu                                                         Affiliation: USAMVB Timișoara, Facultatea de Medicina Veterinara

The report is an attempt to remember of the updated general principles in the main dermatologic affects topical applications in in dog and cat. Initially are presented: general principles about drug topic formulation application, with the describing of skin’s anatomical bases and functions, active substance’s physic-chemical proprieties, factors that affects transdermal passage, methods of transdermal amplification. Also are presented: characteristics of dog and cat’s skin, skin’s specific vascularisation, ecology and histochemy. In the last chapter are presented the main known dermatologic entities in dog and cat.

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About ATC / DDD drug clasiffication system

Authors: Diana Iacob (Obistioiu)1, Maria Andresescu2, Romeo T. Cristina1

Affiliation: 1 USAMVB Timișoara, Facultatea de Medicina Veterinara                                                                               2 ANSVSA Bucuresti

The field of drug utilization research has attracted increasing interest since its infancy in the 1960s. At a symposium in Oslo in 1969 entitled The Consumption of Drugs, it was agreed that an internationally accepted classification system for drug consumption studies was needed. At the same symposium the Drug Utilization Research Group (DURG) was established and tasked with the development of internationally applicable methods for drug utilization research. By modifying and extending the European Pharmaceutical Market Research Association (EPhMRA) classification system, Norwegian researchers developed a system known as the Anatomical Therapeutic Chemical (ATC) classification. In order to measure drug use, it is important to have both a classification system and a unit of measurement. To deal with the objections against traditional units of measurement, a technical unit of measurement called the Defined Daily Dose (DDD) to be used in drug utilisation studies was developed. The purpose of the ATC/DDD system is to serve as a tool for drug utilization research in order to improve quality of drug use. One component of this is the presentation and comparison of drug consumption statistics at international and other levels. The classification of a substance in the ATC/DDD system is not a recommendation for use, nor does it imply any judgements about efficacy or relative efficacy of drugs and groups of drugs. The Anatomical Therapeutic Chemical classification system for veterinary medicinal products, ATCvet, has been developed by the Nordic Council on Medicines (NLN) in collaboration with the NLN’s
ATCvet working group, consisting of experts from the Nordic countries. The ATCvet system for the classification of veterinary medicines is based on the same overall principles as the ATC system for substances used in human medicine. In most cases an ATC code exists which can be used to classify a product in the ATCvet system. The ATCvet code is then created by placing the letter Q in front of the ATC code. In some cases, however, specific ATCvet codes are created, e.g. antibacterials for intramammary use (QJ51) and Immunologicals (QI).

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Prohibited anabolic substances, dangerous to human consumers, in accordance of E.U. regulations

Authors: Flavia A. Hanganu1, V. Voicu2, R. T. Cristina1

Affiliation:  1 USAMVB Timisoara,                                                                                                                                 2 I.C.P.B.M.U.V. Bucuresti

Substances with anabolic effects are used to enhance feed conversion, growth rate or muscle tissue deposition in stock farming for several decades. The majority of these compounds have biochemical effects similar to sex steroids (androgens, estrogens, gestagens). However, in the E.U., the use of hormones for growth – promotion or fattening is prohibited. Monitoring of residues of hormonal growth-promotion in meat or milk, is essential for implementing such bans and to protect public health against the harmful effects of these substances, which incidentally is found in products of animal origin.

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