The classical swine fever vaccine – Pestivac M® – dosage in wild boars baits

Authors: Știrbu C., Valeria Gruia, Stănuică D., Militaru D                                                                   Affiliation: S.N. Institutul Pasteur, Bucuresti

The work presents the technical dates about vaccine baits and the results of domestic and feral pigs immunization against classical swine fever using these vaccine baits. The new vaccine contains modified swine fever virus grown on tissue culture encapsulated in blisters, which are incorporated into cereal-based and attractive flavors matrix measuring 4 x 4 x 1.5 cm. The new vaccine administered to domestic and feral pigs was well-accepted. Thirty days after administration more than 75% of the vaccinated feral pigs and 100% of the vaccinated domestic pigs showed good antibody levels. Further more 80% of the vaccinated domestic pigs were protected after challenged with virulent CFS virus 30 days post vaccination. The vaccine can be administered any time during the year.

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Researches on efficiency of Romvac’s company live vaccines used in rabies imunoprophylaxy in canides

Authors: Gugiu I.1, Chiriaca Ionescu I.N.1, Stiube P.1, Toacsen E. 1, Mihai I.2, Zavoiu F. 1, Motiu Gh.1,                         Mirela Vasile1, Ana Sandu3, Daniela Motiu3, Botea D.3

Affiliation: 1 Romvac Company S.A.                                                                                                                                    2 Institutul de Diagnostic si Sănătate Animală                                                                                                     3 Institutul pentru Controlul Produselor Biologice si Medicamentelor de uz Veterinar

The paper present the methods for preparation and control of the live rabies vaccines, RABIROM and RABIROM -V, produced by ROMVAC Co. S.A., to be used for prevention of the rabies in dogs, cats and foxes.

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In vitro testing of the some antibiotics efficiency on some E. coli strains isolated from avian farms

Authors: Veturia-Ileana Nueleanu, A. Chis                                                                                             Affiliation: USAMV Cluj-Napoca, Facultatea de Medicina Veterinara

For broiler chickens, a major mortality cause on the entire exploitation period is represented by the collibacilar infections, which need a correct and efficient treatment. The mortality in 94 broiler chickens was studied, between three and thirty days of age, from four avian farms from Satu-Mare county, isolating and identifying 32 Escherichia coli strains in pure culture. The testing of sensitivity to antibiotics of the isolated germs was made through the difusimethric method, revealing a decreased efficiency to Oxitetracyclin, Amoxicyllin and Erithromycin, while in the case of Amoxicyllin + Clavulanic acid, Florfenicol and Gentamycin a good sensitivity was observed.

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E.U. veterinary drug’s legislation

Author: Romeo T. Cristina                                                                                                                   Affiliation: USAMVB Timișoara, Facultatea de Medicina Veterinara

The paper makes a short intoduction in veterinary drug’s legislation and presents de functioning mechanisms of European Medicines Agency (EMEA). There are presented EMEA’s structure, responsabilities, EU topic definitions and other specific aspects.

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Molecular action mechanisms of the immunomodulators

Author: Cristian Belteghi                                                                                                               Affiliation: S.N. Institutul Pasteur S.A. Bucuresti

The special attention paid, during the last period, to researches on immunomodulators and on the possibilities of the immune response unspecific manipulation represent an answer to the more and more stringent needs of finding out complementary and/or alternative solutions to the classic therapeutic methods. With this work, we intended to present synthetically the progress recorded in the field of molecular mechanisms that represent the base for the effects exerted by various categories of immunomodulator products. The imunomodulator mechanisms performed through Toll-like receptors, receptors for cytokines, receptors for hormones and through calcineurin have been described in this paper work.

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Cat’s external otitis – diagnose and treatment

Author: Janos Degi                                                                                                                       Affiliation: USAMB Timisoara, Facultatea de Medicină Veterinară

Otitis externa is a frequent finding in cats, with a prevalence rate of 2-10 % of all feline patients seen in general practice. Otodectes cyanotis, the ear mite, is responsible for approximately 50% of all feline otitis externa cases. However, other infectious and inflammatory conditions frequently either cause or predispose the cat to ear disease. In 20-30 % of chronic feline ear cases the initiating cause remains unknown.

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Therapy in alergy and anaphylaxis

Author: Romeo T. Cristina                                                                                                     Affiliation: USAMVB Timișoara, Facultatea de Medicina Veterinara

Paper emphasises the main therapeutic aspects in allergy and anaphylaxis to animals. There are presented the specific mechanisms an also the efficient therapeutic groups.

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Anthelmintic control strategies for equines strongylidosis

Author: Mihai Cernea                                                                                                                     Affiliation: USAMV Cluj-Napoca, Facultatea de Medicină Veterinara

Equine strongylidosis study is a worldwide highly important topic due to the serious consequences this disease can induce both by simptomathology and by decreasing physical capacity of animals. Strongyls presence may modify behavior, fertility, physical condition, organism development through maturity, decreases resistance to other phatogenous agents and may even become the cause of death. Due to extension and prejudices these diseases can inflict, diagnosis of parasite invasions has to be made even for those with sub clinical evolution. This diagnosis must be followed by exact identification of the etiological agent involved as well as its genetical, biological and ecological characteristic, and also the possible resistance to specific medication, taking in to account the selection of certain antiparasitary medicine with enhanced efficacy. Regardless of the medicine or dehelmintization programme used, systematic investigation of resistant helminthes populations must constitute a sine qua non condition in modern parasitology.

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Therapeutic surveillance and the optimization of pharmacotherapy

Author: Maria Crivineanu                                                                                                             Affiliation: USAMV Bucuresti, Facultatea de Medicină Veterinară

Based on initial therapeutic efficiency surveillance, pharmacotherapy optimisation constitues a feed-back mechanism, necessary for an efficient, sure and individualised pharmacotherapy.

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Diagnosticul si tratamentul dermatitei atopice la carnivore

Author: Gheorghe Solcan                                                                                                             Affiliation: USAMV Iasi, Facultatea de Medicina Veterinara

Atopy is defined as a type I hypersensitisation reaction, due to the genetic predisposition of some individuals to produce specific IgE and/or IgGd excessively after the contact with different aeroallergens inhaled and/or transdermal or digestively absorbed. The paper reveals the main methods of diagnose and therapy of the carnivore’s atopy.

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