Use of antibiotics and about quinolones in veterinary therapy

Authors: Cristina T. Romeo, Doma O. Alexandru, Moșneang C. Laura                                                          Affiliation: USAMVB, Faculty of Veterinary Medicine Timisoara

In Romania are being done extensively efforts in the veterinarians education to emphasize the importance and the European regulations familiar behavior, relating to veterinary drugs prescribing, the issues of residues, of antibacterial resistance and of judicious use of the veterinary conditionigs. In this respect, the present synthesis presents an overview, a useful and necessary bibliographical remembrance to veterinary practitioner about antibiotics and quinolones in particular. Are summarized: bacterial antagonism, methods for studying the effectiveness of antibiotics, the mode of action of antibiotics, the phenomenon of resistance to antibiotics and toxic secondary phenomena caused by antibiotics, continued by information about quinolone-carbonic acid derivatives (quinolones) them action mechanism, classification and presentation of the main representatives, indications and contraindications, etc. Referate is conceived in two parts about antibiotics and about quinolones.

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The methodology of setting up and the management of antibiotic treatments in veterinary medicine

Author: Anca Mărculescu                                                                                                                         Affiliation: USAMV Cluj-Napoca, Facultatea de Medicina Veterinara

Antibiotic therapy represents one of the most frequently used methods in medical practice, human or veterinary. The efficiency of this therapy is based on an appropriate choose of antibiotics, avoiding also the errors that may occur by their utilization. Sometimes, the association of antibiotics is recommended, in order to reduce the antibiotic resistance and also to increase the efficacy of antibiotics in veterinary practice.

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In vitro testing of the some antibiotics efficiency on some E. coli strains isolated from avian farms

Authors: Veturia-Ileana Nueleanu, A. Chis                                                                                             Affiliation: USAMV Cluj-Napoca, Facultatea de Medicina Veterinara

For broiler chickens, a major mortality cause on the entire exploitation period is represented by the collibacilar infections, which need a correct and efficient treatment. The mortality in 94 broiler chickens was studied, between three and thirty days of age, from four avian farms from Satu-Mare county, isolating and identifying 32 Escherichia coli strains in pure culture. The testing of sensitivity to antibiotics of the isolated germs was made through the difusimethric method, revealing a decreased efficiency to Oxitetracyclin, Amoxicyllin and Erithromycin, while in the case of Amoxicyllin + Clavulanic acid, Florfenicol and Gentamycin a good sensitivity was observed.

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Antibiotics: mechanisms of action

Author: Anca Mărculescu                                                                                                             Affiliation: USAMV Cluj-Napoca, Facultatea de Medicină Veterinară

The antibiotics are a very important class of chemotherapeutic agents that are capable to stop or even selectively destroy pathogens in man and animal. Antimicrobial agents affect susceptible organisms in various ways. The major mechanisms of action of antibiotics are: inhibition of cell wall synthesis, impairment of cell membrane function, inhibition of protein synthesis, inhibition of nucleic acids synthesis.

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Resistance to antibiotics

Authors: Anca Mãrculescu, M. Cernea, Veturia Nueleanu, N.A. Oros, R. Chereji                                 Affiliation:  USAMVB Cluj-Napoca, Faculty of Veterinary Medicine

The antibiotics represent the most important therapeutic arsenal in the fight against pathogen microorganisms. Even in the beginning of their use, there was registered bacterial resistance, phenomenon that became an alarming subject in the last decades. There are some types of resistance to antibiotics that are influenced by many factors. The resistance term can be used as microbiological resistance and clinical resistance. The resistance to antibiotics can be a natural phenomenon or a gained one. The mechanisms of gaining resistance in bacteria are genetic or biochemical. Because of the fact that this is an increasing phenomena, data about antibiotic resistance is a permanent necessity in any part of the world.

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