The thyroid and the thyroid hormones

Authors:    Andreea Pap, Crina Mosneang, Romeo T. Cristina
Affiliation: Faculty of Veterinary Medicine Timisoara

The thyroid gland is located in the cervical fascia were it is divided in two lateral lobes, right and left, disposed on both sides of the trachea, and unlike other vertebrates, the cat does not have an isthmus that connects the two lobes. The main products of secretion of the thyroid gland are represented by thyroxine [T4] and 3,5,3 ‘triiodothyronine [T3]. To these are added other hormones resulted from the deiodination of the principle hormones. This process is catalized by the D1, D2 and D3 deiodinase resulting 3,3,5′ triiodothyronine [rT3], 3,5-T2, 3,3’-T2 or 3’,5’-T2 which by further deiodination will form 3-3’- T1 and T1. To reach this deiodination must be followed certain steps in the hormon synthesis transport path, and it is important the present of the carrier protein. Once inside the tissue, the concentration of each hormone will vary depending on the binding site and the metabolic processes that will be followed.

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Diagnostic guide methods in the feline hyperthyroidism

Authors: Andreea Pap, Florin Simiz, Andreia Chirila, Romeo T. Cristina
Affiliation: Faculty of Veterinary  Medicine Timisoara

Given the multifactorial etiology of this endocrinopathies, the confirming the diagnosis of hyperthyroidism encountered many difficulties over the years, not only due to the necessity of medical knowledge, as well as the lack of ability to perform various laboratory tests more or less accessible. So far the methods most commonly used are available: free dosing or total thyroid hormone, triiodothyronine suppression test and one of the methods require special equipment but is not accessible in our country yet for cats is scintigraphy.

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Pharmacotherapy of hyperthyroidism in cats

Authors: Andreea Pap and Romeo T. Cristina                                                                               Affiliation: Faculty of Veterinary Medicine Timișoara

Currently, the feline hyperthyroidism possesses three types of treatment that includes medication, surgery and radioactive therapie. The success of these therapies consists in obtaining favorable results, by inhibiting thyroid hormone secretion, reducing clinical signs, improving the live’s quality and by absence of side effects of administered medication. One of these three therapies that fulfill these conditions and considered ideal for clinicians is the radiation therapy. Choosing this therapy depends not only on the availability of radioiodine licensed clinics or the presence of a skilled surgeon but also on the patient’s clinical condition, especially when a cardiovascular or renal disease is present in this review paper.

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