Use of antibiotics and about quinolones in veterinary therapy

Authors: Cristina T. Romeo, Doma O. Alexandru, Moșneang C. Laura                                                          Affiliation: USAMVB, Faculty of Veterinary Medicine Timisoara

In Romania are being done extensively efforts in the veterinarians education to emphasize the importance and the European regulations familiar behavior, relating to veterinary drugs prescribing, the issues of residues, of antibacterial resistance and of judicious use of the veterinary conditionigs. In this respect, the present synthesis presents an overview, a useful and necessary bibliographical remembrance to veterinary practitioner about antibiotics and quinolones in particular. Are summarized: bacterial antagonism, methods for studying the effectiveness of antibiotics, the mode of action of antibiotics, the phenomenon of resistance to antibiotics and toxic secondary phenomena caused by antibiotics, continued by information about quinolone-carbonic acid derivatives (quinolones) them action mechanism, classification and presentation of the main representatives, indications and contraindications, etc. Referate is conceived in two parts about antibiotics and about quinolones.

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UE organisms for the reglementation and market’s maintenance of veterinary use products

Authors: Lolita Taban, Iuliana Moloiu                                                                                             Affiliation: Institutul pentru Controlul Produselor Biologice si Medicamentelor de uz Veterinar

Following the Romania’s EU accession in 2007, national legislation licensing, distribution and circulation of veterinary medicinal products has been harmonized with relevant Community legislation, namely Directive 2001/82 amended by Directive 2004/28 and translated by Order of ANSVSA no.187/2007 (which amended the Order ANSVSA no. 69/2005). Institute for the Control of Biological Products and Veterinary Medicines (ICBMV) is the competent authority in the licensing of veterinary medicinal products, working with European institutions, notably the European Medicines Agency (EMEA), in matters related to the licensing and post-marketing surveillance, together with ANSVSA. In the up mentioned context, ICBMV representatives attending to meetings of Working Groups of the CVMP (Committee for Medicinal Products for Veterinary Use) and the Coordination Group for Mutual Recognition production and decentralized procedure (CMDv), on different fields. Working groups are meeting in sessions, quarterly, and the CVMP and CMDv Committees meetings are held monthly, according to a timetable. By participating to the work meetings, the ICBMV representatives have the opportunity to improve their knowledge in them specific areas and to receive up to date information in the field of the veterinary medicinal products. Also, the information received is transmitted to the Romanian pharmaceutical industry for implementing the new UE requirements, to ensure an adequate level of quality, safety and efficacy in the field of veterinary medicinal products.

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New alternatives in veterinary anthelminthic therapy

Author: Romeo T. Cristina                                                                                                             Affiliation: USAMVB Timisoara, Faculty of Veterinary Medicine.

Present paper proposes the presentation of antiparasitic boluses, veterinary use specific conditionings with importance in gastro intestinal helminth population control, as a modern alternative to the classic antihelmintic therapy. The active substances are released consecutive to: diffusion, osmotic procesess, to progressive erosion, or through electronic programmed devices. Anthelmintic boluses are classified upon the releasing system in: a) anthelmintic sustained release systems: for albendazole (Proftril bolus), morantel tartrate (Paratect flex and bolus) ivermectines (Enzec and Alzet, Ivomec SR Bolus), levamisole (Chronominthic bolus), oxfendazol (Synanthic multidose bolus) fenbendazole (Panacur Bolus). b) anthelmintic programmed periodic release systems: Intra Ruminal Pulse Release Electronic Device (I.R.P.R.E.D) and Repidose (Autoworm, Oxfendazole Pulsed Release Bolus).

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